Abstract: Connecting theoretical models for exotic quantum states to real materials is a key goal in quantum materials synthesis. Two-dimensional model systems have been proposed to host a wide variety of exotic phases- historically a number of techniques have been used to realize these including thin film growth and mechanical exfoliation. We describe here our recent progress in experimentally realizing 2D model systems using bulk crystal synthesis including superconducting and topological states. We discuss their structures and the new phenomena that they support. We comment on the perspective for realizing further 2D model systems in complex material structures and their connections to other methods for realizing 2D systems.