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Chaos & Complex Systems Seminar
Systems Virology: Models and measures of virus growth and infection spread
Date: Tuesday, September 13th
Time: 12:05 pm
Place: 4274 Chamberlin
Speaker: John Yin, WI Department of Chemical & Biological Engineering Systems Biology Theme, Wisconsin Institute for Discovery
Abstract: Viruses infect humans and cause diseases such as AIDS, hepatitis, cancer, and influenza, annually impacting the health of a major fraction of the world's population. Basic science has revealed the molecular functions encoded by many viruses of biomedical importance, but relatively little progress has been made toward understanding how the individual functions of a virus contribute to the integrated processes of virus growth and infection spread. We have begun to address this deficiency by developing quantitative experiments and mathematical models to describe the growth and spread of vesicular stomatitis virus (VSV), a rabies-like virus that can be readily cultured in the laboratory. This talk will highlight our recent progress toward coupling the roles of both biological amplification and physical movement in the growth and spread of virus infections. Advances from the work have applications toward the development of more potent vaccines, anti-viral therapies, as well as virus-based therapies to treat cancer.&lt;br&gt;<br>
Host: Clint Sprott
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