Abstract: I will present results from a study of the minimal supersymmetric standard model (MSSM) with minimal flavor violation (MFV), imposing constraints from flavor physics observables and MSSM Higgs searches, in light of the recent discovery of a 125 GeV Higgs boson by ATLAS and CMS. We analyzed the electroweak vacuum stability conditions to further restrict the MSSM parameter space. In addition, we showed a connection to ultraviolet physics via an implementation of renormalization group running, which determines the TeV-scale spectrum from a small set of minimal supergravity parameters. Finally, we investigated the impact from dark matter direct detection searches. Our work highlights the complementarity of collider, flavor and dark matter probes in exploring the MSSM, and shows that even in a MFV framework, flavor observables constrain the MSSM parameter space well beyond the current reach of direct SUSY particle searches.